How we are building the future’s
polymer systems
for drug delivery and surface modification
![](https://pendantbio.com/wp-content/uploads/2019/03/polymer-system-cube-1.jpg)
Multiple variables presented in addressing product needs
![](https://pendantbio.com/wp-content/uploads/2019/03/polymer-system-cube-2.jpg)
First generation systems may be able to tune in on some parameters
![](https://pendantbio.com/wp-content/uploads/2019/03/polymer-system-cube-3.jpg)
Pendant Bio offers the next generation technology – providing independent tuning parameters to meet the needs of the industry
Our tunable polymers outperform traditional biocompatible matrices.
![](https://pendantbio.com/wp-content/uploads/2019/03/single-adjustemnt-polumer.png)
PLGA and other common polymer chemistries can be flexible, but are limited, first generation drug delivery systems. Their features can be adjusted one or two at a time, allowing only for incremental progress in drug delivery.
![](https://pendantbio.com/wp-content/uploads/2019/03/tunable-polymer-1.png)
Pendant’s solution is a completely modular platform with multiple features and functions that can be simultaneously customized. This allows for alterations in porosity, drug loading & release, and rates of degradation.
Functionality makes the polymers you know… better.
- Polyesters, polycarbonates, polyglycidols
- Biodegradable via hydrolysis
- Biocompatible and non-toxic
- Reproducible synthesis
- Predictable synthesis
- Easy to source materials
![Cross Linkers](/wp-content/uploads/2019/03/cl-1.jpg)
![Cross Linkers](/wp-content/uploads/2019/03/cl-5.jpg)
Valerolactone
![Cross Linkers](/wp-content/uploads/2019/03/cl-2.jpg)
![Cross Linkers](/wp-content/uploads/2019/03/cl-6.jpg)
Caprolactone
![Cross Linkers](/wp-content/uploads/2019/03/cl-3.jpg)
![Cross Linkers](/wp-content/uploads/2019/03/cl-7.jpg)
Butyrolactone
![Cross Linkers](/wp-content/uploads/2019/03/cl-4.jpg)
![Cross Linkers](/wp-content/uploads/2019/03/cl-8.jpg)
Glycolide/Lactide
![](https://pendantbio.com/wp-content/uploads/2019/06/crosslinker-1.png)
Polyesters, polycarbonates, polyglycidols
Biodegradable via hydrolysis
Biocompatible and non-toxic
Biodegradable via hydrolysis
Biocompatible and non-toxic
Reproducible synthesis
Predictable synthesis
Easy to source materials
Predictable synthesis
Easy to source materials
![](https://pendantbio.com/wp-content/uploads/2019/06/crosslinker-1.png)
Our molecular architecture adds versatility to polymer systems
![](https://pendantbio.com/wp-content/uploads/2019/03/cl-9.jpg)
Pendant functionalities – R:
![Cross Linkers](/wp-content/uploads/2019/03/cl-10.jpg)
Allyl
![Cross Linkers](/wp-content/uploads/2019/03/cl-11.jpg)
Propargyl
![Cross Linkers](/wp-content/uploads/2019/03/cl-12.jpg)
Epoxide
- Pendant functionalities provide an unlimited number of conjugation/post-modifications to polymer backbones such as:
- Covalent cross-linking
- Targeting ligand conjunction
- Diverse manufacturing and formulation methods available
- Compatible with broad range of therapeutics
- Capable of nano, micro, and macro materials
- Versatile platform for drug delivery, coatings, biomaterials, and other polymer applications
- Strong intellectual property