How we are building the future’s
polymer systems
for drug delivery and surface modification
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Multiple variables presented in addressing product needs
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First generation systems may be able to tune in on some parameters
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Pendant Bio offers the next generation technology – providing independent tuning parameters to meet the needs of the industry
Our tunable polymers outperform traditional biocompatible matrices.
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PLGA and other common polymer chemistries can be flexible, but are limited, first generation drug delivery systems. Their features can be adjusted one or two at a time, allowing only for incremental progress in drug delivery.
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Pendant’s solution is a completely modular platform with multiple features and functions that can be simultaneously customized. This allows for alterations in porosity, drug loading & release, and rates of degradation.
Functionality makes the polymers you know… better.
- Polyesters, polycarbonates, polyglycidols
- Biodegradable via hydrolysis
- Biocompatible and non-toxic
- Reproducible synthesis
- Predictable synthesis
- Easy to source materials
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Valerolactone
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Caprolactone
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Butyrolactone
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Glycolide/Lactide
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Polyesters, polycarbonates, polyglycidols
Biodegradable via hydrolysis
Biocompatible and non-toxic
Biodegradable via hydrolysis
Biocompatible and non-toxic
Reproducible synthesis
Predictable synthesis
Easy to source materials
Predictable synthesis
Easy to source materials
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Our molecular architecture adds versatility to polymer systems
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Pendant functionalities – R:
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Allyl
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Propargyl
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Epoxide
- Pendant functionalities provide an unlimited number of conjugation/post-modifications to polymer backbones such as:
- Covalent cross-linking
- Targeting ligand conjunction
- Diverse manufacturing and formulation methods available
- Compatible with broad range of therapeutics
- Capable of nano, micro, and macro materials
- Versatile platform for drug delivery, coatings, biomaterials, and other polymer applications
- Strong intellectual property